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Process for the preparation of optionally substitu

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专利名称:Process for the preparation of optionally

substituted 2,3- indolinediones

发明人:Gary M. Coppola申请号:US05/966200申请日:19781204公开号:US04212804A公开日:19800715

摘要:An improved process for the preparation of optionally substituted 2,3-indolinediones which are useful as intermediates in the preparation of compounds havingpharmacological activity which comprises reacting a 3,1- benzoxazine with an alkali oralkaline earth metal cyanide or a tetra-(C. sub.1-4) alkylammonium cyanide to obtain a 2-imino- 3-indolinone, which is then subjected to hydrolysis.

申请人:SANDOZ INC

代理人:Gerald D. Sharkin,Richard E. Vila,Joseph J. Borovian

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