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Assay for the free portion of substances in biolog

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专利名称:Assay for the free portion of substances in

biological fluids

发明人:Brockas, Anthony John申请号:EP83305988.4申请日:19831003公开号:EP0106615A2公开日:19840425

摘要:@ An assay for the free portion of an analyte, present in a biological fluid whichalso contains the analyte bound to natural binders, comprises incubating a sample of thefluid with a specific binder for the analyte and an antibody to the specific binder wherebythe analyte and the antibody are caused to compete for binding sites on the specificbinder. The antibody is preferably an anti-idiotype antibody to the specific binder. One ofthe specific binder and the antibody is labelled, whereby the proportion of the labelledreagent bound to its binding partner can be measured and used to determine the freeanalvte concentration in the samole.

申请人:AMERSHAM INTERNATIONAL plc

地址:White Lion Road Amersham Buckinghamshire, HP7 9LL GB

国籍:GB

代理机构:Pennant, Pyers

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