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专利名称：Method for determining the effectiveness of
stabilized chlorine dioxide in a mouth rinse
发明人：James L. Ratcliff,Elizabeth A. Renken,Jessica
K. Ward
申请号：US117747申请日：20070709公开号：US07875460B2公开日：20110125
专利附图：
摘要：A method for determining the available treatment dosage of stabilized chlorinedioxide in the prevention and the treatment of plaque accumulation, volatile sulfur
compound production, gingivitis and periodontitis, and for differentiating the treatmentdosage from other chlorine-containing compounds that may not have such beneficialeffects is disclosed. When in solution as stabilized chlorine dioxide, the presence of otherions such as chlorate and chloride may not only obscure results as to the concentrationof stabilized ClO, but also reduce the predicted effectiveness. The present invention usesvalidated analytical methods to predict the effectiveness of stabilized ClOby moreprecisely measuring its concentration in solution. Such measurement renders precision ata level required of food-grade and pharmacy-grade chemotherapeutic agents in the oralcavity. Preferred concentrations are within the range of about 0.005 to about 2% (w/v)stabilized chlorine dioxide. The solution may be in the form of wash, rinse, soak, paste,gel, aerosol spray, or other suitable delivery system.
申请人：James L. Ratcliff,Elizabeth A. Renken,Jessica K. Ward
地址：Pueblo West CO US,Peoria AZ US,Tempe AZ US
国籍：US,US,US
代理机构：The von Hellens Law Firm, Ltd.
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